Desiré Buckley, Assistant Professor

Fetal Alcohol Spectrum Disorders, Neurobiology, Genetics, Zebrafish, Gene-Environment Interactions

Ph.D., 2015, University of Missouri - Columbia

Office: LSW 528


Specific Interests

Research in my lab focuses on the adverse effects of prenatal alcohol exposure on neuronal cell behaviors during embryonic neurodevelopment. Using zebrafish as a model organism, we combine live imaging and several molecular techniques to analyze neuronal cell movements in embryos exposed to alcohol. The goal of my research is to investigate mechanisms underlying aberrant neuronal cell behaviors, which are highly variable as a result of complex interactions between genes and alcohol. Thus, my lab also employs genetics alongside embryology and molecular biology to elucidate how genes and the environment can modify the susceptibility of different neuronal subpopulations to alcohol.


Selected Publications (full list here)

  • Sidik A, Dixon G, Buckley DM, et al. 2021. Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway. BMC Biol. 19, 134. doi:10.1186/s12915-021-01062-9
  • Buckley DM, Sidik A, Kar RD, Eberhart JK. 2019. Differentially sensitive neuronal subpopulations in the central nervous system and the formation of hindbrain heterotopias in ethanol-exposed zebrafish. Birth Defects Research doi:10.1002/bdr2.1477
  • Fernandes Y, Buckley DM, Eberhart JK. 2017. Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. Biochem. Cell Biol. 17:1-10. doi:10.1139/bcb-2017-0122